Tuesday, 8 July 2014

Ebola virus disease (EVD) or Ebola hemorrhagic fever (EHF)

Patient suffering from Ebola 


EBOLA!!! Sounds like someone's native name doesn't it? Anyways I'm pretty sure most of y'all have heard about this virus but had a friend who's sister got infected by this deadly virus and passed on, so i decided to do a little review on the said disease. Before I begin I'll want to refresh our minds with the term "DISEASE"

WHAT IS A DISEASE:

disease is a particular abnormal,pathological condition that affects part or all of an organism. It is often construed as a medical condition associated with specific symptoms and signs. It may be caused by factors originally from an external source, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune diseases. In humans, "disease" is often used more broadly to refer to any condition that cause paindysfunction,distress,social problems, or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries,disabilities,disorders,syndromes,infections, isolated symptoms, deviant behaviors, and a typical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories. Diseases usually affect people not only physically, but also emotionally, as contracting and living with many diseases can alter one's perspective on life, and one's personality.
 
TYPES OF DISEASES:
- Contagious
-Non-contagious

contagious disease is a subset category of infectious diseases(or communicable diseases), which are easily transmitted by physical contact (hence the name-origin) with the person suffering the disease, or by their secretions or objects touched by them.
The non-contagious category of infectious/communicable diseases usually require a special mode of transmission between hosts. These include need for intermediate vector species (mosquito that cause malaria) or transfer of bodily fluid (such as transfusions, needle-sharing or sexual contact).

BRIEF HISTORY:

Ebola first appeared in 1976 in 2 simultaneous outbreaks, in Nzara, Sudan, and in Yambuku, Democratic Republic of Congo. The latter was in a village situated near the Ebola River, from which the disease takes its name.The Ebola virus is one of two members of a family of viruses that is designated as the Filoviridae. Although naturally occurring, some public health experts worry that the lethality of the virus makes it an attractive potential bioterrorism agent. Under natural circumstances Ebola induced hemorrhagic fever carriers have such high death rates that their rapid death actually acts to limit the spread of the virus. Deliberate spread of the virus would counteract this natural limiting factor.

 
WHAT IS EBOLA AND HOW DOES IT SPREAD :
 
Ebola virus disease(EVD) orEbola hemorrhagic fever(EHF) is the human disease caused by ebola viruses. Ebola virus is one of at least 30 known viruses capable of causing viral hemorrhagic fever syndrome.Symptoms start two days to three weeks after contracting the virus with a fever, throat and muscle pains, and headaches. There is then nausea, vomiting and diarrhea along with decreased functioning of the liver and kidneys. At this point some people begin to have problems with bleeding.The disease is first acquired by a population when a person comes into contact with the blood or bodily fluids of an infected animal such as a monkey or fruit bat. Fruit bats are believed to carry and spread the disease without being affected by it. Once infection occurs, the disease may be spread from one person to another. Men who survive may be able to transmit the disease sexually for nearly two months. To make the diagnosis, typically other diseases with similar symptoms such as malaria,cholera and other viral hemorrhagic fever are excluded. The blood may then be tested for either antibodies to the virus, the viral DNA, or the virus itself to confirm the diagnosis.

SIGNS & SYMPTOMS:

Rapid effect of Ebola begins abruptly with a sudden onset of an influenza-like stage characterized by general malaise, fever with chills, sore throat, severe headache, weakness, joint pain, muscle pain, and chest pain. Respiratory tract involvement is characterized by pharyngitis with sore throat, cough,dyspnea, and hiccups. The central nervous system is affected as judged by the development of severe headaches,agitation, confusion,fatigue,depression,seizures, and sometimes coma. In general we have :
FEVER, NAUSEA, HEADACHE, TIREDNESS, DIARRHOEA, COUGHING, HERMOHHAGE.

CAUSES OF EBOLA:

EVD is caused by four of five viruses classified in the genus Ebolavirus, family Filoviridae, order Mononegavirales: Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV),Taï Forest virus (TAFV). The fifth virus, Reston virus (RESTV), is thought to be not disease causing for humans and therefore not discussed here.EVD is believed to occur after an ebola virus is transmitted to a human index case via contact with an infected animal host. Human-to-human transmission occurs via direct contact with blood or bodily fluids from an infected person (including embalming of an infected dead person) or by contact with contaminated medical equipment such as needles.In the past, explosive nosocomial transmission has occurred in under-equipped African hospitals due to the reuse of needles and lack of implementation of universal precautions. Aerosol transmission has not been observed during natural EVD outbreaks.The potential for widespread EVD epidemics is considered low due to the high case-fatality rate, the rapidity of demise of patients, and the often remote areas where infections occur.The average time between contracting the infection and the onset of symptoms is 13 days, but can be as long as 25 days.

PREVENTIVE MEASURES OF EBOLA:
Controlling Reston ebolavirus in domestic animals
No animal vaccine against RESTV is available. Routine cleaning and disinfection of pig or monkey farms (with sodium hypochlorite or other detergents) should be effective in inactivating the virus.
If an outbreak is suspected, the premises should be quarantined immediately. Culling of infected animals, with close supervision of burial or incineration of carcasses, may be necessary to reduce the risk of animal-to-human transmission. Restricting or banning the movement of animals from infected farms to other areas can reduce the spread of the disease.
As RESTV outbreaks in pigs and monkeys have preceded human infections, the establishment of an active animal health surveillance system to detect new cases is essential in providing early warning for veterinary and human public health authorities.

Reducing the risk of Ebola infection in people
In the absence of effective treatment and a human vaccine, raising awareness of the risk factors for Ebola infection and the protective measures individuals can take is the only way to reduce human infection and death.
In Africa, during EVD outbreaks, educational public health messages for risk reduction should focus on several factors:
  • Reducing the risk of wildlife-to-human transmission from contact with infected fruit bats or monkeys/apes and the consumption of their raw meat. Animals should be handled with gloves and other appropriate protective clothing. Animal products (blood and meat) should be thoroughly cooked before consumption.
  • Reducing the risk of human-to-human transmission in the community arising from direct or close contact with infected patients, particularly with their bodily fluids. Close physical contact with Ebola patients should be avoided. Gloves and appropriate personal protective equipment should be worn when taking care of ill patients at home. Regular hand washing is required after visiting patients in hospital, as well as after taking care of patients at home.
  • Communities affected by Ebola should inform the population about the nature of the disease and about outbreak containment measures, including burial of the dead. People who have died from Ebola should be promptly and safely buried.

WHAT TO DO WHEN ALREADY INFECTED (TREATMENT):

No ebolavirus-specific treatment exists. Treatment is primarily supportive in nature and includes minimizing invasive procedures, balancing fluids and electrolytes to counter dehydration, administration of anticoagulants early in infection to prevent or control disseminated intravascular coagulation, administration of procoagulants late in infection to control hemorrhaging, maintaining oxygen levels, pain management, and administration of antibiotics or antimycotics to treat secondary infections.
Best advices i could give are:
  1. Call your medical centre and tell them about your illness
  2. Listen to the solutions they have to offer carefully. You may as well be taken to a special hospital.
  3. Keep away from others so they don't get sick.
  4. Be especially careful of your vommit and diarrhoea.

CONCLUSION:

EBOLA is a dangerous disease,As an outbreak of ebola progresses, bodily fluids from diarrhea, vomiting, and bleeding represent a hazard. Due to lack of proper equipment and hygienic practices, large-scale epidemics occur mostly in poor, isolated areas without modern hospitals or well-educated medical staff. Many areas where the infectious reservoir exists have just these characteristics. In such environments, all that can be done is to immediately cease all needle-sharing or use without adequate sterilization procedures, isolate patients, and observe strict barrier nursing procedures with the use of a medical-rated disposable face mask, gloves, goggles, and a gown at all times, strictly enforced for all medical personnel and visitors.The aim of all of these techniques is to avoid any person’s contact with the blood or secretions of any patient, including those who are deceased.


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